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29.Hwang, N. S., Varghese, S., Elisseeff, J. H. "Direct differentiation of human embryonic stem cell and formation of cartilage tissue" PLoS One (in press, 2008)

28. Hwang, N. S., Hwang, Y., Vrghese, S., "Mesenchymal stem cell differentiation, and regenrative medicine" (submitted)

27. Hwang, N.S., Varghese, S., Zhang, Z., and Elisseeff, J. H. "In vivo heterotypic osseous tissue formation of mesenchymal stem cells derived from human embryonic stem cells," PNAS (under revision)

26. Varghese, S., Ferran, A., Hwang, N.S., Hillel, A., Theprungsirikul, P., Canver, C. A., Zhang, Z., Shamblott, M., Gearhart, J., and Elisseeff, J. H. "Engineering musculoskeletal tissue by human embryonic germ cell derivatives," (submitted)

25.Hwang, N. S., Varghese, S.,Li, H., Elisseeff, J. H. "Extracellular microenvironment regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells" (submitted)

24. Lee, H. J., Chansakul, T., Varghese, S., Hwang, N. S., Elisseeff, J. H. "The effect of immobilized HA binding peptide on cartilage engineering in hydrogels" (submitted)

23. Lee, H. J., Yu, C., Chansakul, T., Varghese, S., Hwang, N. S., Elisseeff, J. H. "Enhanced Chondrogenic Differentiation of Embryonic Stem Cells by Co-Culture with Hepatic cells" Stem Cell Dev. (in press,2008)

22. Varghese, S., Hwang, N.S., Canver, C. A., Lin, D., Theprungsirikul, P., and Elisseeff, J. H. "Chondroitin sulfate based hydrogel niche for chondrogenic differentiation of mesenchymal stem cells," Matrix Biology, 27, 12 (2008)

21. Hwang, N. S., Varghese, S., Elisseeff, J. H. "Controlled differentiation of stem cells," Adv. Drug Deliver. Rev. 60, 199 (2008)

20. Lee, H. J., Yu, C., Chansakul, T., Hwang, N., Varghese, S., and Elisseeff, J. H. "Enhanced chondrogenesis of mesenchymal stem cells in collagen mimetic peptide-modified microenvironment," submitted

19. Wang, D. A., Varghese, S., Strehin, I., Gorham, J., Cascio, B., Gurken, I., and Elisseeff, J. H. "Multifunctional chondroitin sulfate for tissue integration," Nature Materials, 6, 385 (2007) Highlighted by Science (editorÕs choice, v. 316. p. 1099, 2007)

18. Hwang, N.S., Varghese, S., Sampattavanich, S., Theprungsirikul, P., Canver, C. A., Sharma, B., and Elisseeff, J. H. "Response of zonal chondrocytes to extracellular matrix hydrogels," FEBS Lett.581, 4172 (2007)

17. Lee, H. J., Varghese, S., Hwang, N., and Elisseeff, J. H. "Nanoengineered Hydrogels for Cartilage Tissue Engineering," in Micro- and Nanoengineering of the Cell Microenvironment Technologies and Applications, Artech House Publishing Inc., in press (2007)

16. Hwang, N. S., Varghese, S., Puleo, C., Zhang, Z., and Elisseeff, J. H. "Morphogenetic signals from chondrocytes promote chondrogenic and osteogenic differentiation of Mesenchymal stem cells in vitro and in vivo," J. Cell. Physiol., 212, 281 (2007)

15. Varghese, S., Theprungsirikul, P., Sahani, S., Hwang, N.S., Yarema, K.J., and Elisseeff, J.H. "Glucosamine modulates chondrocyte proliferation, matrix production and gene expression," Osteoarth. Cartilage, 15, 59 (2007) Rated as one of the ÒhottestÓ paper that appeared in Osteoarth. Cartilage in the field of Medicine and Dentistry by Science Direct (http://top25.sciencedirect.com/)

14. Hwang, N.S., Varghese, S., and Elisseeff, J. H. "Cartilage tissue engineering: Directing differentiation of embryonic stem cells in 3D cultures," Methods Mol Biol (Stem Cell Assays), 407, 351 (2007)

13. Varghese, S., Theprungsirikul, P., Ferran, A., Hwang, N.S., Canver, A., and Elisseeff, J.H "Chondrogenic differentiation of human embryonic germ cell derived cells in hydrogels," IEEE EMB Eng Med and Biol, 1, 2643 (2006)

12. Hill, D. A., and Varghese, S. "On the implementation of time-temperature superposition: Thermorheologically simple materials," submitted

11. Varghese, S., and Elisseeff, J. H. ÒHydrogels for musculoskeletal tissue engineering,Ó Adv. Polym. Sci. 203, 95 (2006)

10. Varghese, S*, Hwang, N. S*, Theprungsirikul, P., Canver, A., and Elisseeff, J.H. "Enhanced chondrogenic differentiation of murine embryonic stem cells in hydrogels with glucosamine," Biomaterials 27, 6015 (2006) [*authors contributed equally]

9. Elisseeff, J. H., Ferran, A., Hwang, S., Varghese, S., and Zhang, Z. "The role of biomaterials in stem cell differentiation: Applications in the musculoskeletal system," Stem Cells Dev. 15, 295 (2006)

8. Hwang, N.S., Varghese, S., Zhang, Z., and Elisseeff, J. H. "Chondrogenic differentiation of human embryonic stem cell-derived cells in arginine-glycine-aspartate-modified hydrogels," Tissue Eng. 12, 2695 (2006)

7. Varghese, S., Lele, A. K., and Mashelkar, R. A. "Metal-ion-mediated healing of gels," J. Polym. Sci. Polym. Chem. 44, 666 (2006)

6. Varghese, S., Lele, A. K., Srinivas, D., Sastry, M., and Mashelkar, R. A. "Novel macroscopic self-organization in polymer gels," Adv. Mater. 13, 1544 (2001)
Rated as the best paper amongst all engineering papers from CSIR laboratories in India in 2001
Appeared as a cover story in News India Magazine (Nature Publishing Group)

5. Varghese, S., Lele, A. K., Srinivas, D., and Mashelkar, R. A. "Role of hydrophobicity on structure of polymer-metal complexes," J. Phys. Chem. B 105, 5368 (2001)

4. Varghese, S., Lele, A. K., and Mashelkar, R. A. "Designing new thermoreversible gels by molecular tailoring of hydrophilic-hydrophobic interactions," J. Chem. Phys. 112, 3063 (2000)
Featured in News India Magazine (Nature Publishing Group)

3. Varghese, S., Lele A. K., and Mashelkar, R. A. "Effect of polymer-metal complexation on the phase transition of thermoreversible copolymer gels," J. Phys. Chem. B 103, 9530 (1999)

2. Bhalerao, V. S., Varghese, S., Lele, A. K., and Badiger, M. V. "Thermo reversible hydrogel based on radiation induced copolymerization of poly(N-isopropyl acrylamide) and poly(ethylene oxide)," Polymer 39, 22 (1998)

1. Badiger, M. V., Lele, A. K., Bhalerao, V. S., Varghese, S., and Mashelkar, R A. "Molecular tailoring of thermo-reversible copolymer gels: Some new mechanistic insights," J. Chem. Phys. 109, 1175 (1998)

PATENTS
U. S Patent (patent no. 6,794,467): Process for preparation of polymeric absorbents