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Development of sensors to continuously monitor blood
and tissue lactate concentration. |
 |
ˇ
Development of bioinstrumentation using
microelectronics to produce battery-operated portable
electrochemical instrumentation to telemeter and log data from
sensors. |
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Monitoring continuously lactate metabolism in the
heart during studies of ischemia. |
 |
ˇ
Using lactate and oxygen continuous measurements in
the evaluation of blood substitutes in animal models of hemorrhage
and resuscitation. |
 |
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Development of sensors to detect pyruvate
concentration in biological media, that is for use in bioreactors,
the bloodstream, and within tissue fluids of the body. |
 |
ˇ
Development of a stable oxygen sensor that can be used
in conjunction with adaptive rate pacemakers for patients with heart
disease. |
 |
ˇ
Microbial production and purification of highly stable
and active enzymes for use in sensors. |
